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Epitalon

Epitalon (also spelled Epithalon) is the pineal bioregulator tetrapeptide Ala-Glu-Asp-Gly (AEDG), molecular weight approximately 390 Da, modeled on the pineal polypeptide complex epithalamin. It was developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology, and it is the most extensively studied member of the peptide bioregulator class.

Its AEDG sequence places it in the Ala-Glu-Asp (AED) structural family shared with Cartalax, Bronchogen, Cardiogen, and Cortagen, each differing only in the fourth residue. What sets Epitalon apart within that family is its research subject rather than its structure: it is the one bioregulator studied primarily for telomerase activity and telomere-length regulation, alongside circadian and melatonin-related signaling and antioxidant response. As with the rest of the class, the published work is predominantly preclinical and concentrated in the originating laboratory.

Supplied as a lyophilized 10-vial 10mg kit for in vitro research use only.