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Repair
TB-500
Thymosin Beta-4 Fragment
TB-500 is a synthetic fragment corresponding to the actin-binding region of Thymosin Beta-4, a naturally occurring regenerative protein. It is a core subject of cytoskeletal and tissue-remodeling research and a common counterpart to BPC-157 in combination studies.
Preclinical and in vitro research focuses on actin sequestration and regulation, cell migration, angiogenesis, and extracellular-matrix signaling. The actin-binding mechanism is what sets TB-500 apart from BPC-157: where BPC-157 is studied primarily for angiogenic and cytoprotective effects, TB-500 is examined for its role in cytoskeletal dynamics and cell motility. Supplied as a lyophilized 10-vial 10mg kit for in vitro research use only.
$385
1
$385
per 10-vial kit
$3.85 / mg
Research Library
TB-500 Research Review →
Mechanism, evidence level & in vitro context
Certificate of Analysis
Available upon request. Custom and large batch orders include a batch-specific COA.
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⚠ For in vitro research use only.
Not for human or animal consumption. Not evaluated by the FDA.
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Common Questions
TB-500 FAQ
What is TB-500?+
TB-500 is a Thymosin Beta-4 Fragment supplied for laboratory research. Thymosin Beta-4 fragment studied in vitro for actin regulatory pathway analysis, extracellular matrix signaling mechanisms, and cytoprotective response research.
What is the difference between TB-500 and Thymosin Beta-4?+
TB-500 is a synthetic peptide corresponding to the active actin-binding region of the naturally occurring protein Thymosin Beta-4 (TB4). It is studied for actin regulation and tissue-repair signaling.
What is lyophilized TB-500, and how is it reconstituted?+
TB-500 is supplied as a lyophilized (freeze-dried) powder, a dehydrated form that keeps the peptide stable during shipping and storage. In the laboratory it is reconstituted (returned to liquid form) using a solvent such as bacteriostatic water, added slowly against the side of the vial, which is then swirled gently, never shaken, until the powder fully dissolves. All handling is for in vitro research use only.
How should TB-500 be stored?+
Store the lyophilized TB-500 powder at -20°C, protected from light and moisture, where it remains stable long-term. Once reconstituted, keep it refrigerated (2-8°C) and use it within the timeframe appropriate for your research protocol.
What is the purity of TB-500, and how is it tested?+
Every batch of TB-500 is produced to a purity of 99% or higher. Purity and molecular identity are verified using standard analytical methods: high-performance liquid chromatography (HPLC) to measure purity, and mass spectrometry (MS) to confirm the peptide's molecular weight.