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Melanocortin
MT-1
Melanotan I
MT-1 (Melanotan I, afamelanotide) is a linear analogue of alpha-melanocyte-stimulating hormone (alpha-MSH). It is studied for comparatively selective activation of the melanocortin-1 receptor (MC1R), which distinguishes it from the broader, more potent receptor activity of MT-2.
In vitro and preclinical research focuses on MC1R binding and activation, melanogenesis and eumelanin synthesis signaling, and photoprotective pathways in melanocyte models. Its narrower receptor profile makes it the reference compound when researchers isolate MC1R-driven pigmentation signaling from the wider melanocortin effects seen with MT-2. Supplied as a lyophilized 10-vial 10mg kit for in vitro research use only.
$350
1
$350
per 10-vial kit
$3.50 / mg
Research Library
MT-1 Research Review →
Mechanism, evidence level & in vitro context
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Available upon request. Custom and large batch orders include a batch-specific COA.
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⚠ For in vitro research use only.
Not for human or animal consumption. Not evaluated by the FDA.
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Common Questions
MT-1 FAQ
What is MT-1?+
MT-1 is a Melanotan I supplied for laboratory research. Linear alpha-MSH analogue studied in vitro for melanocortin-1 receptor activation pathway modeling, photoprotective signaling mechanism analysis, and pigmentation response research.
What is the difference between Melanotan 1 and Melanotan 2?+
Melanotan I (afamelanotide) is a linear alpha-MSH analogue selective for the MC1 receptor, whereas Melanotan II is a cyclic, less-selective analogue that also acts on other melanocortin receptors. MT-1 is the more receptor-selective of the two.
What is lyophilized MT-1, and how is it reconstituted?+
MT-1 is supplied as a lyophilized (freeze-dried) powder, a dehydrated form that keeps the peptide stable during shipping and storage. In the laboratory it is reconstituted (returned to liquid form) using a solvent such as bacteriostatic water, added slowly against the side of the vial, which is then swirled gently, never shaken, until the powder fully dissolves. All handling is for in vitro research use only.
How should MT-1 be stored?+
Store the lyophilized MT-1 powder at -20°C, protected from light and moisture, where it remains stable long-term. Once reconstituted, keep it refrigerated (2-8°C) and use it within the timeframe appropriate for your research protocol.
What is the purity of MT-1, and how is it tested?+
Every batch of MT-1 is produced to a purity of 99% or higher. Purity and molecular identity are verified using standard analytical methods: high-performance liquid chromatography (HPLC) to measure purity, and mass spectrometry (MS) to confirm the peptide's molecular weight.