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Neuropeptide
Semax
ACTH-Derived Neuropeptide
Semax is a synthetic heptapeptide derived from the ACTH(4-10) fragment, developed as a neuroactive research peptide with no corticotropic (adrenal) activity. Its neuropeptide lineage without hormonal action is the feature that defines it within cognitive-peptide research.
In vitro and preclinical work focuses on BDNF (brain-derived neurotrophic factor) expression and signaling, neuroprotective and neurotrophic pathways, dopaminergic and serotonergic modulation, and responses to oxidative and ischemic stress models. It is frequently studied alongside Selank as a paired nootropic research tool with a distinct mechanism. Supplied as a lyophilized 10-vial 10mg kit for in vitro research use only.
$280
1
$280
per 10-vial kit
$2.80 / mg
Research Library
Semax Research Review →
Mechanism, evidence level & in vitro context
Certificate of Analysis
Available upon request. Custom and large batch orders include a batch-specific COA.
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⚠ For in vitro research use only.
Not for human or animal consumption. Not evaluated by the FDA.
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Common Questions
Semax FAQ
What is Semax?+
Semax is a ACTH-Derived Neuropeptide supplied for laboratory research. ACTH-derived heptapeptide studied in vitro for neuroprotective pathway modeling, BDNF signaling mechanism analysis, and neurological response research.
What is Semax derived from?+
Semax is a synthetic heptapeptide based on a fragment of the ACTH(4-10) sequence. Developed in Russia, it is studied in vitro for neuroprotective and BDNF-related signaling.
What is lyophilized Semax, and how is it reconstituted?+
Semax is supplied as a lyophilized (freeze-dried) powder, a dehydrated form that keeps the peptide stable during shipping and storage. In the laboratory it is reconstituted (returned to liquid form) using a solvent such as bacteriostatic water, added slowly against the side of the vial, which is then swirled gently, never shaken, until the powder fully dissolves. All handling is for in vitro research use only.
How should Semax be stored?+
Store the lyophilized Semax powder at -20°C, protected from light and moisture, where it remains stable long-term. Once reconstituted, keep it refrigerated (2-8°C) and use it within the timeframe appropriate for your research protocol.
What is the purity of Semax, and how is it tested?+
Every batch of Semax is produced to a purity of 99% or higher. Purity and molecular identity are verified using standard analytical methods: high-performance liquid chromatography (HPLC) to measure purity, and mass spectrometry (MS) to confirm the peptide's molecular weight.